Department for the preclinical assessment of medical devices

Proposing new treatment solutions prior to clinical trials

Prior to a clinical trial, it is vital to assess innovative technological strategies in terms of their operability and ensure that the medical devices developed will not have harmful effects. To this end, suitable models are developed, particularly using large animals of an appropriate size for most medical devices designed for humans.

This is carried out at the Preclinical Assessment Department, using the following equipment:

  • Preclinical operating rooms for rodent and large animal surgery
  • Preclinical 4.7 T MRI, for rodent and primate imaging
  • Experimental and behavioral study rooms
  • Animal supply facility (small animals, mice and rats, pigs and primates)
  • Electrophysiology
  • FLI- and IBISA- approved intravital optical imaging platform located in the Preclinical Assessment Department (two-photon optical imaging equipment)

All studies are carried out under the supervision of an independent ethics committee and the site’s body tasked with overseeing animal welfare, in strict compliance with regulatory requirements.

Activities

The Preclinical Assessment Department draws on an array of multidisciplinary skills to carry through preclinical research projects, always in accordance with animal ethics. A vet, animal technicians and specialized technicians ensure the well-being of the animals used in scientific research by the researchers, doctors, biologists, engineers and mathematicians.

Using suitable animal models, the department validates the effectiveness and harmlessness of new diagnostic and therapeutic concepts. For this, they have a unique technical platform which facilitates the multimodal approach applied within a designated area.

This platform specializes in large animal models used for translational research, helping to fast-track the transfer of new technology developed for patients.